From I-5 Heading South:
As you approach downtown San Diego from the north on I-5, take the FRONT STREET/ CIVIC CENTER exit.  Stay to the right.  Merge onto FRONT STREET and head south for three blocks to ASH STREET.  Turn right onto ASH STREET and go west 3 blocks to COLUMBIA STREET.  Turn left on COLUMBIA STREET and go south 2 1⁄4 blocks.  Turn right into the 550 Corporate Center parking garage (across the street from Karl Strauss Brewery and Grill).

From I-5 Heading North:
As you approach downtown San Diego from the south on I-5, take the CIVIC CENTER exit.  On the exit ramp, stay to the left.  Turn left onto B STREET.  Head west on B STREET all the way to the Civic Center.  At the Civic Center, turn right onto 3rd AVENUE and head north for two blocks to ASH STREET.  Turn left onto ASH STREET and head west for 6 blocks to COLUMBIA STREET.  Turn left on COLUMBIA STREET and go south 2 1⁄4 blocks. Turn right into the 550 Corporate Center parking garage (across the street from Karl Strauss Brewery and Grill).

From I-805 Heading South:
Approaching San Diego from the north on I-805, take the CA-163 SOUTH exit toward DOWNTOWN and pass through Balboa Park.  As CA-163 SOUTH comes to an end, take the ASH STREET exit and head west on ASH STREET for 12 blocks to COLUMBIA STREET.  Turn left on COLUMBIA STREET and head south for 2 1⁄4    blocks.  Turn right into the 550 Corporate Center parking garage (across the street from Karl Strauss Brewery and Grill).

From the Airport (Lindbergh Field):
As you depart the airport, head east on HARBOR DRIVE toward DOWNTOWN.  Stay on HARBOR DRIVE, which gradually curves to the right heading south.  Approximately two miles from the airport, just after you pass the cruise ship passenger terminal on your right, turn left on BROADWAY and head east three blocks to INDIA STREET.  Turn left onto INDIA STREET and head north for two blocks to B STREET.  Turn right onto B STREET and head east for one block to COLUMBIA STREET.  Turn right onto COLUMBIA STREET and head south for just 1⁄4 block. Turn right into the 550 Corporate Center parking garage (across the street from Karl Strauss Brewery and Grill).